abstract：:In this study, cellulose nanocrystals (CNCs) with PEG grafts of various lengths (1 k, 2 k, 5 k, and 10 kDa) were prepared via a polydopamine (PDA) mediated method in the aqueous solution. The prepared CNC-PEGs were further used to reinforce the polyvinyl alcohol (PVA) at the loading of 0, 1, 3, 5, and 7 wt% in order t...

authors： Zheng T,Clemons CM,Pilla S

更新日期：2021-11-01 00:00:00

abstract：:In this work, an integrated 3-dimensional microfluidic device was developed for simulation of the immune microenvironment of glioma niche through the co-culture of three kinds of related cells. Glioma cells, endothelial cells and macrophages were co-cultured together in the microfluidic device, spatially separated by ...

authors： Lin L,He Z,Jie M,Lin JM,Zhang J

更新日期：2021-11-01 00:00:00

abstract：:We developed a simple and highly-selective method for 5-methylcytosine detection of specific gene sequence based on binary-probe DNA hybridization. The sequence complementary to the target was designed into two probes, and each fragment of binary probes bound to a relatively short sequence of the target, which made it...

authors： Zhong XY,Zhou QY,Dong JH,Yu Y,Zhou YL,Zhang XX

更新日期：2021-11-01 00:00:00

abstract：:In this paper, we propose a self-assembled graphene oxide (GO)/Ag NPs SERS Raman sensor based on a novel type of optofluidic MHF as a point-of-care testing (POCT) device. This device is used to diagnose jaundice and its related diseases through on-line detection of free bilirubin content in human serum. This optofluid...

authors： Gao D,Yang X,Teng P,Luo M,Zhang H,Liu Z,Yang J,Li Z,Wen X,Yuan L,Li K,Bowkett M,Copner N

更新日期：2021-11-01 00:00:00

abstract：:We developed a methodology for rapid quantification of extracellular neurotransmitters in mouse brain by PESI/MS/MS and longitudinal data analysis using the R and Stan-based Bayesian state-space model. We performed a rapid analysis for quantifying extracellular l-glutamic acid (L-Glu) and gamma-aminobutyric acid (GABA...

authors： Kawakami D,Tsuchiya M,Murata T,Iguchi A,Zaitsu K

更新日期：2021-11-01 00:00:00

abstract：:Heavy metal pollution in the environment poses a serious threat to the ecosystem and human health, which has attracted widespread attention. In this study, an octahedral structure composite composed of UiO-66-NH2 MOFs and semiconductor GaOOH materials has been prepared and used as electrode materials successfully. The...

authors： Ru J,Wang X,Cui X,Wang F,Ji H,Du X,Lu X

更新日期：2021-11-01 00:00:00

abstract：:The current research endeavor aimed to accomplish hypoxia-responsive polyethyleneimine-conjugated carboxymethyl pullulan-based co-polymer (CMP-HA-NI-PEI-NBA) bearing nitroaromatic subunits to efficiently deliver erlotinib (ERL) to reverse its hypoxia-induced resistance in cancer cells. As compared to a control co-poly...

authors： Bera H,Abosheasha MA,Ito Y,Ueda M

更新日期：2021-11-01 00:00:00

abstract：:This study investigated the impact of heterogeneity of crosslinking on a range of physical and mechanical properties of calcium alginate networks formed via external gelation with 0.25-2% sodium alginate and 2.5 and 5% CaCl2. Crosslinking in films with 1-2% alginate was highly heterogeneous, as indicated by their lowe...

authors： Girón-Hernández J,Gentile P,Benlloch-Tinoco M

更新日期：2021-11-01 00:00:00

abstract：:Mercury and sulfur dioxide (SO2) are common pollutants in the ecological environment, which are important factors causing many diseases of organisms. The lack of appropriate analytical tools has limited the further understanding of the relationship between ionic mercury (Hg2+) and SO2. Herein, a bifunctional fluoresce...

authors： Liu J,Li J,Tang J,Yang X,Zhang D,Ye Y,Zhao Y

更新日期：2021-11-01 00:00:00

abstract：:Racemic α-amino acid standards for chiral metabolomics were prepared from l-α-amino acids using a hydrophobic pyridoxal derivative, namely 3-hydroxy-2-methyl-5-((octyloxy)methyl)isonicotinaldehyde (OPy), as the racemization catalyst. Among the 19 tested proteinogenic amino acids, 13 (including the generally unstable a...

authors： Harada M,Shimbo K,Karakawa S

更新日期：2021-11-01 00:00:00

abstract：:A novel coronavirus (COVID-19) has globally attracted attention as a severe respiratory condition. The epidemic has been first tracked in Wuhan, China, and has progressively been expanded in the entire world. The growing expansion of COVID-19 around the globe has made X-ray images crucial for accelerated diagnostics. ...

authors： Jalali SMJ,Ahmadian M,Ahmadian S,Khosravi A,Alazab M,Nahavandi S

更新日期：2021-11-01 00:00:00

abstract：:We propose a high dimensional Bayesian inference framework for learning heterogeneous dynamics of a COVID-19 model, with a specific application to the dynamics and severity of COVID-19 inside and outside long-term care (LTC) facilities. We develop a heterogeneous compartmental model that accounts for the heterogeneity...

authors： Chen P,Wu K,Ghattas O

更新日期：2021-11-01 00:00:00

abstract：:Bacterial attachment to biomaterials is of great interest to the medical and dental field due to its impact on dental implants, dental prostheses, and others, leading to the need to introduce methods for biofilm control and mitigation of infections. Biofilm adhesion is a multifactorial process and involves characteris...

authors： Kreve S,Reis ACD

更新日期：2021-11-01 00:00:00

abstract：:COVID-19 leads to radiological evidence of lower respiratory tract lesions, which support analysis to screen this disease using chest X-ray. In this scenario, deep learning techniques are applied to detect COVID-19 pneumonia in X-ray images, aiding a fast and precise diagnosis. Here, we investigate seven deep learning...

authors： Vieira P,Sousa O,Magalhães D,Rabêlo R,Silva R

更新日期：2021-11-01 00:00:00

abstract：:Cushing's syndrome (CS) is a rare disease caused by chronic and excessive cortisol secretion. When adrenocorticotropin hormone (ACTH) is measurable, autonomous adrenal cortisol secretion could be reasonably ruled out in a differential diagnosis of CS. ACTH-dependent CS accounts for 80%-85% of cases and involves cortis...

authors： Pinelli S,Barbot M,Scaroni C,Ceccato F

更新日期：2021-11-01 00:00:00

abstract：:This study investigated the in vitro bioactivities of extracts obtained from viscera, spines, shells, and gonads of Stomopneustes variolaris using subcritical water extraction (SWE) at 110 °C, 150 °C, 190 °C, and 230 °C and Soxhlet extraction. The highest amounts of phenolics (22.68 ± 0.05 mg GAE/g), flavonoids (27.11...

authors： Chamika WAS,Ho TC,Roy VC,Kiddane AT,Park JS,Kim GD,Chun BS

更新日期：2021-11-01 00:00:00

abstract：:A simple and fast method was developed for the simultaneous determination of 75 plastic food contact material (FCM) in liquid food simulants, at levels of a few ng g-1. The method employs an optimised salt-assisted liquid-liquid extraction for all EU-regulated ethanol/H2O food simulants, in the presence of 10% NaCl (s...

authors： Tsochatzis ED,Lopes JA,Gika H,Dalsgaard TK,Theodoridis G

更新日期：2021-11-01 00:00:00

abstract：:Although betanin is commonly used as a water-soluble red colorant in foods, it is unstable when heated. In this study, the discoloration of betanin in a buffer solution was kinetically studied in the pH range of 2.6 to 7.6 at 40 °C to 80 °C. The absorption spectrum of betanin was deconvoluted into the spectra of betan...

authors： Miyagawa Y,Fujita H,Adachi S

更新日期：2021-11-01 00:00:00

abstract：:To overcome the poor water solubility of curcumin, a curcumin-β-cyclodextrin (Cur-β-CD) complex was prepared as a novel photosensitizer. Fourier-transform infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC), and X-ray diffraction (XRD) were used to verify the formation of Cur-β-CD. Furthermore, the ...

authors： Lai D,Zhou A,Tan BK,Tang Y,Sarah Hamzah S,Zhang Z,Lin S,Hu J

更新日期：2021-11-01 00:00:00

abstract：:Alterations in surface chemical composition relating to rehydration properties of spray-dried camel milk powders during accelerated storage (11-33% RH, 37 °C) over 18 weeks were investigated. The results showed that the surface of the fresh spray-dried camel milk powder (t = 0) was dominated by lipids (78%), followed ...

authors： Ho TM,Ton TT,Gaiani C,Bhandari BR,Bansal N

更新日期：2021-11-01 00:00:00

abstract：:A method for rapid screening and quantification of progesterone and progestins in milks by ultrahigh-performance liquid chromatography coupled with quadrupole-high field Orbitrap high-resolution mass spectrometry (UHPLC QE HF HRMS) was established. Milks samples were extracted by acetonitrile + hexane (80 + 20), purif...

authors： Decheng S,Xia F,Zhiming X,Shulin W,Shi W,Peilong W

更新日期：2021-11-01 00:00:00

abstract：:In this study, the concentration of furan and 2-methylfuran in espresso coffee (EC) obtained from Arabica and Robusta coffee varieties was determined as a function of specific particle size. The particle size and coffee variety significantly influenced the level of furan and 2-methylfuran. In Arabica variety, furan an...

authors： Genovese A,De Vivo A,Aprea A,Cristina Tricarico M,Sacchi R,Sarghini F

更新日期：2021-11-01 00:00:00

abstract：:Antibiotics are widely used in the prevention and treatment of infectious diseases in animals due to its bactericidal or bacteriostatic action. Residual antibiotics and their metabolites pose great threats to human and animal health, such as potential carcinogenic and mutagenic effects, and bacterial resistances. Ther...

authors： Zhou C,Zou H,Sun C,Li Y

更新日期：2021-11-01 00:00:00

abstract：:Despite the challenges in managing the COVID-19 pandemic waves in different contexts and capacities, the vaccines that were recently approved for use have created a window of hope to fight this pandemic more effectively by achieving herd immunity. However, the rates of vaccination coverage vary considerably between co...

authors： Al-Tammemi AB,Tarhini Z

更新日期：2021-11-01 00:00:00

abstract：:Two collagens were made from giant salamander (Andrias davidianus) skin by using acid and pepsin extraction methods. The yields of acid-soluble and pepsin-soluble collagens were 26.9 and 58.7%, respectively. The results of spectrum, electrophoresis and amino acid analysis showed that they were type 1 collagen with two...

authors： Chen X,Jin W,Chen D,Dong M,Xin X,Li C,Xu Z

更新日期：2021-11-01 00:00:00

abstract：:As a fullerene derivative, IC70BA is widely used in the ternary organic solar cells (TOSCs) to increase the open circuit voltage (Voc) of the devices. Unfortunately, most of the literature shows that IC70BA will lead to a reduction in the short-circuit current density (Jsc) and fill factor (FF). In this work, IC70BA i...

authors： Li C,Li W,Sun X,Wang J,Tao J,Zou Z,Liao G,Zou X,Ni J,Zhang J

更新日期：2021-11-01 00:00:00

abstract：:The authors report the preparation of the nanocomposite comprising of vanadium pentoxide (V₂O5) and selenium (Se) nanoparticles and functionalized multiwalled carbon nanotubes (MWCNTs) (V₂O5@Se NPs/MWCNTs). Since Se NPs possesses extraordinary physicochemical properties including larger surface area with higher adsorp...

authors： Francklin Philips M,Thangarathinam J,Princy J,Crispin Tina CA,Crispin Tina CA,Kasthuri A

更新日期：2021-11-01 00:00:00

abstract：:Here, we report the structural and electronic modification induced in chemical vapor deposited graphene by using swift heavy ions (70 MeV Ni6+).Raman spectroscopy was used to quantify the irradiation-induced modification in vibrational properties. The increase in defect density with fluence causes an increase in the i...

authors： Kasana PK,Shakya J,Mohanty T

更新日期：2021-11-01 00:00:00

abstract：:Nanomaterials, such as magnetic nanoparticles have attracted significant attention of medical area due to their capacity to improve the performance of immunoassays. Therefore the aim of this work was to study the bovine serum albumin (BSA) conjugation in superparamagnetic (MNPs)/poly(methyl methacrylate) (PMMA) nanopa...

authors： Feuser PE,Guindani C,Possato JC,Guessi JP,Cordeiro AP,Machado-de-Ávila RA,Sayer C,de Araújo PHH

更新日期：2021-11-01 00:00:00

abstract：:For the development of drugs that treat SARS-CoV-2, the fastest way is to find potential molecules from drugs already on the market. Unfortunately, there is currently no specific drug or treatment for COVID-19. Among all structural proteins in SARS-CoV, the spike protein is the main antigenic component responsible for...

authors： Cardoso EF,Giacomello TF,Rocha de Oliveira LL,da Silva TA,de Jesus Chaves Neto AM,Da Silva Mota GV,Souza Siqueira MR,Paranhos Costa FL

更新日期：2021-11-01 00:00:00

abstract：Objectives:Mortality statistics on the COVID-19 pandemic have led to widespread concern and fear. To contextualise these data, we compared mortality related to COVID-19 during the first wave of the pandemic across seven countries in Europe with all and common causes of death, stratifying by age and sex. We also calcula...

authors： Olabi B,Bagaria J,Bhopal SS,Curry GD,Villarroel N,Bhopal R

更新日期：2021-11-01 00:00:00

abstract：Background:The oral health-promoting effects of green tea are attributed to its polyphenol components. Aim of this work was to systematically review the literature in search for clinical trials assessing green tea for managing periodontitis and caries. Methods:Randomized clinical trials comparing the efficacy of green...

authors： Mazur M,Ndokaj A,Jedlinski M,Ardan R,Bietolini S,Ottolenghi L

更新日期：2021-11-01 00:00:00

abstract：Objectives:One of the many challenges public health practitioners have faced during the COVID-19 pandemic is deciding on the optimal allocation of limited healthcare resources. The current paper addresses the normative question of how medical resources can be optimally distributed during the current pandemic. Methods:...

authors： Yuk-Chiu Yip J

更新日期：2021-11-01 00:00:00

abstract：:Peripheral nerve injuries occur as the result of sudden trauma and lead to reduced quality of life. The peripheral nervous system has an inherent capability to regenerate axons. However, peripheral nerve regeneration following injury is generally slow and incomplete that results in poor functional outcomes such as mus...

authors： Zhang RC,Du WQ,Zhang JY,Yu SX,Lu FZ,Ding HM,Cheng YB,Ren C,Geng DQ

更新日期：2021-11-01 00:00:00

abstract：:Tinnitus can be described as the conscious perception of sound without external stimulation, and it is often accompanied by anxiety, depression, and insomnia. Current clinical treatments for tinnitus are ineffective. Although recent studies have indicated that the caudate-putamen nucleus may be a sensory gating area i...

authors： Wang ML,Song Y,Liu JX,Du YL,Xiong S,Fan X,Wang J,Zhang ZD,Mao LQ,Ma FR

更新日期：2021-11-01 00:00:00

abstract：:Stem cell transplantation may represent a feasible therapeutic option for the recovery of neurological function in children with hypoxic-ischemic brain injury; however, the therapeutic efficacy of bone marrow-derived mesenchymal stem cells largely depends on the number of cells that are successfully transferred to the...

authors： Sun C,Zhang AD,Chen HH,Bian J,Liu ZJ

更新日期：2021-11-01 00:00:00

abstract：:Implant-related esthetic demands have increased tremendously in recent years. The presence of shallow papillae or open interproximal spaces (black triangles) are some of the most troubling dilemmas in dentistry. Among the many factors associated with the presence of papilla or papilla height, the interproximal bone is...

authors： Urban IA,Barootchi S,Tavelli L,Wang HL

更新日期：2021-11-01 00:00:00

abstract：Objectives:An outbreak of the novel coronavirus in December 2019 caused a worldwide pandemic. This disease also impacts European countries, including Germany. Without effective medicines or vaccines, non-pharmaceutical interventions are the best strategy to reduce the number of cases. Study design:A deterministic mode...

authors： Chadsuthi S,Modchang C

更新日期：2021-11-01 00:00:00

abstract：:Green leafy vegetables (GLVs) are a key element of healthy eating patterns and are an important source of lutein. To clarify the evidence for associations between GLVs and lutein intake and multiple health outcomes, we performed a review. A total of 24 meta-analyses with 29 health outcomes were identified by eligibili...

authors： Li N,Wu X,Zhuang W,Xia L,Chen Y,Wang Y,Wu C,Rao Z,Du L,Zhao R,Yi M,Wan Q,Zhou Y

更新日期：2021-10-30 00:00:00

abstract：:Bioremediation of pesticides in contaminated foodstuffs using probiotics has attracted great attention in recent years, but some intermediate products may have profound effects on the toxicity of treated food. Therefore, this work studied the degradation mechanism of dimethoate in milk by L. plantarum, and analyzed th...

authors： Yuan S,Yang F,Yu H,Xie Y,Guo Y,Yao W

更新日期：2021-10-30 00:00:00